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  • Chemical Biology

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    Item specifics

    Condition:
    New: A brand-new, unused, unopened, undamaged item in its original packaging (where packaging is ... Read moreabout the condition
    Colour: GOLD
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    Does Not Apply

    Country/Region of Manufacture: Taiwan
    For Bike Type: Folding Bike For Brake Type: Direct/Linear Pull (V-Brakes)
    Brand:

    Lixada

    EAN:

    7437505791714

    26 Dual Spring Disc Option Fork 1 1 8 Threadless Bicycle Cruiser Fork CHROME

    Here’s some medicinal chemistry combined with synthetic biology for you. Many people are used to thinking in terms of finding small-molecule probes for various cell targets, and those are valuable things. But what if you want to control a certain population of (for example) ion channels, but there aren’t any compounds that will do the… 2x SNAIL MTB Road XC bike Brake Disc Floating redor 160 180 203mm redors 6 Bolts
  • Chemical News

    3T ARX II Pro 100mm + -17 Alloy Road Stem

    3T Zero 25 Team Stealth Seatpost I was interested to see this paper, which goes into detail on a chemical phenomenon that many have seen but no one understands very well: triboluminescence. That word meets with a blank stare or instant recognition; there’s not much in between. It means “emission of light when a material is physically broken”, and that encompasses… 55lb DWC Dumbbell Hex Rubber Coated, Commercial, Ergonomic Steel Handle, NEW
  • Analytical Chemistry

    70-pound Cast Iron Kettlebell Weight (11 X 8 X 8)

    I suppose I deserve this one. Some years ago on the blog, I wrote about my days in grad school having to learn about symmetries and vibrational spectroscopy. Sparingly has that knowledge come in handy since then, but the course is still a vivid memory for me, since that’s the clearest example I had yet… Read More
  • Cancer

    Making and Measuring Multivalency

    Here’s an unusual paper that’s studying receptor behavior on cell surfaces by use of atomic force microscopy. (Here’s the SI file, which is free to access). The authors took the marketed VEGF inhibitor vandetanib (VD6474) and attached it through linkers to the AFM tip, and then scanned around the surface of live human umbilical v… ACTION 460 3705 BRAKE PAD CANTI BULK (Bag 25)
  • Drug Assays

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    3ttt Mutant Handlebar 3T Vintage Road Bike 44cm c-c dropbar racing NOS A common question – well, it should be a common question, anyway – is “How do I make sure that this compound collection is a useful one to screen?” There are alternative forms that come down to the same issues – if you’re putting together a new focused screening set, what should be in it?… Read More
  • Biological News

  • Business and Markets

  • Analytical Chemistry

    A Close Look at Fragments

    Here’s a look from the D. E. Shaw research team at fragment binding, and even if you don’t do fragment-based drug discovery, it’s worth a read. That’s because the mechanisms by which fragments bind to proteins are most likely the fundamental ones by which larger molecules bind as well; this is the reductionist look at… Read More
  • Analytical Chemistry

  • Academia (vs. Industry)

    Startup Culture, Starting

    3x Phil and Teds DASH PRAM TYRES 12 1 2 x 2 1 4 + Bent tubes + Puncture Sealant Many readers of this blog work in the biopharma industry, naturally, and of those, many are in and around the (few) locations where a great many of the companies in the industry are born. I myself am in the Boston/Cambridge area, famously thick with companies large and small, and then you have the Bay area… 23mm Width SUPERTEAM Carbon Road Wheel 50mm Depth R13 3K Matte Clincher Wheelset
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