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  • Chemical Biology

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    Here’s some medicinal chemistry combined with synthetic biology for you. Many people are used to thinking in terms of finding small-molecule probes for various cell targets, and those are valuable things. But what if you want to control a certain population of (for example) ion channels, but there aren’t any compounds that will do the… E-Bike 24V 27.2Ah Battery Electric Bicycle Bike Decathlon Torker Populo Akkurad
  • Chemical News

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  • Analytical Chemistry

  • Cancer

  • Drug Assays

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    E-Bike 36V 10.4Ah Battery Electric Bicycle Bike Remington Diamond Radon E-Ranger A common question – well, it should be a common question, anyway – is “How do I make sure that this compound collection is a useful one to screen?” There are alternative forms that come down to the same issues – if you’re putting together a new focused screening set, what should be in it?… Read More
  • Biological News

  • Business and Markets

  • Analytical Chemistry

    A Close Look at Fragments

    Here’s a look from the D. E. Shaw research team at fragment binding, and even if you don’t do fragment-based drug discovery, it’s worth a read. That’s because the mechanisms by which fragments bind to proteins are most likely the fundamental ones by which larger molecules bind as well; this is the reductionist look at… Read More
  • Analytical Chemistry

  • Academia (vs. Industry)

    Startup Culture, Starting

    E-Bike 36V 10.4Ah Vélo Electrique Pedelec IBEX EZIP Easybike EBC TREK Alpha Many readers of this blog work in the biopharma industry, naturally, and of those, many are in and around the (few) locations where a great many of the companies in the industry are born. I myself am in the Boston/Cambridge area, famously thick with companies large and small, and then you have the Bay area… EastPoint Sports Tournament 110mm Resin Bocce Lawn Game with Carrier
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